Arvid Chowdhury is a Biomedical Engineering researcher and lecturer with expertise in protein engineering, structural biology, molecular biology, and X-ray crystallography. He currently serves as a Lecturer in the Department of Biomedical Engineering at North South University, where he is involved in undergraduate teaching, laboratory instruction, curriculum-related activities, and the development of lectures, laboratory activities, assessments, and instructional materials.

Mr. Chowdhury holds a Master of Applied Science (MASc) in Biomedical Engineering from the University of Toronto, Canada (2019–2021), where his graduate research focused on the structural characterization of the SMURF2 HECT domain with a high-affinity ubiquitin variant. His research contributed to a peer-reviewed publication in Protein Science on the structural and functional validation of a highly specific SMURF2 inhibitor.

He also holds a Master of Engineering (M.Eng) in Biomedical Engineering from Ryerson University, Canada (2017–2018) and a BSc (Hons.) in Biomedical Science from York University, Canada (2013–2017).

As a biomedical engineering researcher, Mr. Chowdhury worked at the University of Toronto as part of the COVID-19 Rapid Research Program, conducting protein engineering research in the Sidhu Group under a CIHR-funded program. His research involved engineering ubiquitin variants targeting SARS-CoV-2 enzymes and contributing to structural studies of protein–enzyme complexes.

His research and technical expertise includes protein engineering, protein purification, molecular biology, bacterial culture, PCR, ELISA, DNA extraction, transformation and transfection, Western and Southern blotting, SDS-PAGE, gel filtration, and spectrophotometry. His structural biology experience includes X-ray crystallography, molecular replacement, structural refinement, and protein structure analysis.

His academic and research interests lie at the intersection of biomedical engineering, protein science, molecular biology, and structural biology, with a focus on understanding and engineering biological systems through interdisciplinary approaches.

His research interests encompass interdisciplinary areas of Biomedical Engineering and molecular biosciences, including:

• Protein engineering and protein design
• Structural biology
• Molecular biology
• X-ray crystallography
• Protein–protein and protein–enzyme interactions
• Protein structure and function
• Ubiquitin-related protein biology
• Structural characterization of biologically important proteins
• Molecular approaches to therapeutic and biomedical research

• BIO 103 Biology I
• EEE 452 Engineering Economics
• MAT 116 Pre-Calculus
• CHE 101 Chemistry I
• CSE 498/EEE 498/ETE 498 Internship/Co-op/Directed Research

CIHR-Funded COVID-19 Research Program

Mr. Chowdhury participated in the COVID-19 Rapid Research Program at the University of Toronto as a researcher in the Sidhu Group, under a CIHR-funded COVID-19 research program. His work involved:

• Engineering ubiquitin variants targeting SARS-CoV-2 enzymes
• Conducting protein engineering experiments
• Contributing to structural studies of protein–enzyme complexes
• Applying molecular and structural biology approaches to COVID-19-related research

Graduate Research – University of Toronto

As part of his MASc research, Mr. Chowdhury investigated the structure of the SMURF2 HECT domain with a high-affinity ubiquitin variant. This research contributed to the peer-reviewed publication:

Tessier, T. M., Chowdhury, A., et al. (2024). Structural and functional validation of a highly specific Smurf2 inhibitor.Protein Science, 33(2), e4885.